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    Translational Cardiology Molecular Basis of Cardiac Metabolism Cardiac Remodeling Translational Therapies and Imaging Techniques
    Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.
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    Heparin Induced Thrombocytopenia 5th Ed

    Original price was: $200.00.Current price is: $150.00.

    Heparin Induced Thrombocytopenia 5th Ed

    Although first reported in 1973, immune heparin-induced thrombocytopenia (HIT) remains one of the most frequent and devastating adverse drug reactions encountered by physicians. This thoroughly updated fifth edition from international experts Professors Warkentin and Greinacher is the gold standard for accurate diagnosis and management of this condition. Identifying key signs and symptoms and providing clear intervention strategies―including the use of alternative anticoagulants to manage critical circumstances―this is an essential resource for all clinicians and a "must" for hematology consultants.Heparin-Induced Thrombocytopenia, Fifth Edition explores:
    • Clinical and laboratory studies on HIT
    • The immune basis and pathogenesis, animal models, and laboratory testing for HIT antibodies
    • Clinical features, differential diagnosis, scoring systems, and frequency of HIT in diverse clinical settings, including pediatric patients
    • Evidence-based guidelines for recognition, treatment, and prevention
    • Actions that should and should not be taken after the identification of HIT
    • Traditional and novel pharmacotherapies, current dosing guidelines, and the advantages and limitations of alternative anticoagulants
    • Selection criteria from a variety of new treatment options, helping physicians determine which of these agents are safe and effective for their patients
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    Post Genomic Cardiology 2nd Ed

    Original price was: $198.00.Current price is: $150.00.

    Post Genomic Cardiology 2nd Ed

    by José Marín-García  (Author) In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach.This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA.
    • Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches
    • Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome
    • Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs
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    Evidence Based Cardiology Consult

    Original price was: $209.00.Current price is: $150.00.

    Evidence Based Cardiology Consult

    The book will provide a detailed evidence-based approach to key issues in the pathophysiology, diagnosis, and management of patients with concurrent medical issues. It will provide a clinical focus with practical advice on the prevention, diagnosis, and treatment of heart disease supported by an expert’s summary, without duplicating other texts. Each chapter will be structured similarly in the following sections: (1) Introduction, (2) Pathophysiology, (3) Diagnosis (4) Management (5) Key Points, (6) Summary of the key guidelines from professional societies where available. The recommendations will have a firm background in the AHA/ACC or ESC recommendations for the management of patients. The intention is to create a comprehensive book rather than a pocketbook or manual. We hope this book will serve as an up to date reference for the practicing clinician. Each of the approximately 40 chapters will have at most 5000 words and 5 -7 high quality figures or illustrations each. Only the highest quality authors will be recruited from the United States and Europe. The emphasis will be on depth of information yet ease of access. This necessitates an approach whereby not a single word, sentence or page of the book will be wasted. Brief where it needs to be brief, detailed where detail is required, this will be a true all-encompassing clinician reference.
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    Short Stay Management of Atrial Fibrillation

    Original price was: $193.00.Current price is: $150.00.

    Short Stay Management of Atrial Fibrillation

    by W. Frank Peacock (Editor), Carol L. Clark (Editor)This book provides a road map for the efficient and successful management of atrial fibrillation (AF) in the short stay unit. It describes the problem, defines the measures of successful treatment, elucidates interventions, and supplies the tools for achieving quality care. Organized in four parts, it covers the impact of AF on patient populations; the presentation and management of AF; the transition to the outpatient environment; and systems management. Topics include the economic consequences of AF; cardioversion and cardiac implantable electronic devices in AF management; education of the AF patient and discharge planning; and quality metrics in AF. The book also provides order sheets and process criteria with which institutions can successfully manage the AF patient in the short stay unit, thus optimizing patient outcomes, patient satisfaction, and operational efficiencies. Short Stay Management of Atrial Fibrillation is a valuable resource for cardiologists, emergency medicine physicians, electrophysiologists, and other healthcare professionals involved in AF management.
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    Sudden Cardiac Death Predictors Prevalence and Clinical Perspectives

    Original price was: $199.00.Current price is: $150.00.

    Sudden Cardiac Death Predictors Prevalence and Clinical Perspectives

    Sudden Cardiac Death: Predictors, Prevalence and Clinical Perspectives is a detailed clinical compilation on sudden cardiac death causes. From the various geographical regions of the world comes different clinical perspectives toward the SCD problem that shed light on the predictors and estimated prevalence in genetic inheritance worldwide. For many centuries, the mysterious deaths of prominent professional sportsmen have preoccupied the attention of the media and medical professionals. In some cases, it was possible to obtain the medical histories of the victims, data on the presence of some specific diseases, and conditions or potential symptoms preceding the fatal episode. Various rare inherited syndromes that are associated with congenital heart disease are focused on in this study, and the interrelationship between ventricular premature beats, sustained/non-sustained ventricular tachycardias and ventricular fibrillations are discussed. Cardio-oncology is an emerging field where more and more patients face consequences from radiotherapy and chemotherapy because these individuals become more prone to SCD. Among the most notable developments, three-dimensional echocardiography and myocardial strain imaging are worth noting and might inexpensively improve the current risk stratification process. Recently, a strain that reflects the change of length and thickness of myocardial fibres has been incorporated into the routine clinical practice. The risk of sudden cardiac death is not the same in patients with Chagas disease, and newly predicted factors are to blame. The prevalence of SCD, hypertrophic cardiomyopathy and the accurate risk are extremely challenging, so much so that they recently became a source of argument between European and American experts. This is a must-have book for those interested in a clinical approach to the SCD phenomenon.
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    Molecular Sensors for Cardiovascular Homeostasis

    Original price was: $199.99.Current price is: $150.00.

    Molecular Sensors for Cardiovascular Homeostasis

    The biomolecular basis underlying essential hypertension and end organ damage associated with hypertension is characterized as polygenic diseases with complexities such as "environment gene" and "gene-gene" interactions. Despite intensive research in this field, this molecular book is aimed at providing the state-of-the-art reviews which define how the biologic systems sense changes in environment, alter their activities or function, and cross talk with other neurohormonal systems to modulate cardiovascular/renal function and blood pressure. This title will attract scientists and investigators in both academic and industrial fields, and clinicians.
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    Cardiovascular MRI in Practice A Teaching File Approach

    Original price was: $199.00.Current price is: $150.00.

    Cardiovascular MRI in Practice A Teaching File Approach

    Cardiovascular MR imaging has become a robust, clinically useful mod- ity, and the rapid pace of innovation and important information it conveys have attracted many students whose goal is to become adept practitioners. In turn, many excellent textbooks have been written to aid this process. These books are necessary and useful in helping the student learn the underlying pulse sequences used in CMR, as well as the imaging findings in a variety of disorders. However, one of the difficulties inherent in learning CMR from a book is that the printed format is not the ideal medium to d- play the dynamic imaging that comprises a typical CMR case. For instance, it may be difficult to perceive focal areas of wall motion abnormality on serial static pictures, but these abnormalities are often easily seen on cine loops. One might say that trying to learn CMR solely from a standard textbook with illustrations is like trying to learn to drive by looking at snapshots obtained through the windshield of a moving car. The learner needs to see the cardiac motion and decide if it is normal or abnormal; he or she needs to be in the driver’s seat. An additional limitation of the ava- able textbooks on CMR is that while they often have superb illustrations of abnormal findings, these images have been preselected.
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    Platelets in Hematologic and Cardiovascular Disorders A Clinical Handbook

    Original price was: $204.00.Current price is: $150.00.

    Platelets in Hematologic and Cardiovascular Disorders A Clinical Handbook

    A rapid increase in our understanding of the biology of platelets and their role in disease in recent years has been paralleled by increasing successes with established platelet-modifying therapies in many clinical conditions. This text focuses on the clinical role of platelets in a wide variety of hematologic, cardiovascular and other disorders, providing a practical, clinically relevant handbook for all clinicians and researchers interested in platelets and their role in disease. Covering platelet physiology, bleeding disorders, thrombotic disorders and antithrombotic therapy. Chapters cover all the conventional and less conventional aspects of platelet involvement in disease, with an emphasis on recent clinical developments. Clear take home messages have been included in each chapter to aid clinical practice. With contributions from leading experts across three continents, Platelets in Hematologic and Cardiovascular Disorders is an up-to-date, well illustrated, practical resource for everyone involved in clinical practice with platelet disorders.
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    Cardiovascular Disease in Racial and Ethnic Minorities

    Original price was: $204.00.Current price is: $150.00.

    Cardiovascular Disease in Racial and Ethnic Minorities

    by Keith C. Ferdinand (Editor), Annemarie Armani (Editor) 
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    Multimodality Imaging in Cardiovascular Medicine

    Original price was: $209.00.Current price is: $150.00.
    Colour Matt Finshed
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    Cardiovascular Magnetic Resonance: A Companion to Braunwald’s Heart Disease 3rd Edition

    Original price was: $189.00.Current price is: $150.00.
    Colour Matt Finshed
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    Studies on Cardiovascular Disorders

    Original price was: $205.00.Current price is: $150.00.

    Studies on Studies on Cardiovascular Disorders

    by Heinrich Sauer (Editor), Ajay M. Shah (Editor), Francisco R. M. Laurindo (Editor)The role of reactive oxygen species (ROS) in the cardiovascular system is Jan- faced. Whereas low concentrations of ROS are involved in variety of physiological signalling events, oxidative stress resulting from deregulated overproduction of ROS and/or impaired antioxidant defences contributes to cardiovascular disease. The actions of ROS in the cardiovascular system are a fascinating topic, not only for the basic science researcher but also for the clinician who is interested in seeking new therapies for his patients suffering from cardiovascular disease. The current book provides a comprehensive overview of the molecular mechanisms and pathoph- iological settings in which chronic and detrimental oxidative stress arises within the heart and vasculature. The book also considers currently discussed strategies in avoiding chronic redox stress resulting from exposure to risk factors or various cardiovascular interventions. The series starts with an overview by Denise de Castro Fernandes, Diego Bonatto and Francisco Laurindo of redox signaling models that could underlie the dev- opment of redox-associated cardiovascular disorders. The interactions of proteins within signalling cascades with ROS and the regulation of such interactions by the anti-oxidative capacity of the cell are discussed. Rebecca Charles, Joseph Burgoyne and Philip Eaton report on redox-mediated modi cations of proteins under ph- iological and pathophysiological conditions and the variety of post-translational oxidative modi cations that explain redox sensing and signal transduction by proteins at the molecular level. ROS are generated during embryogenesis and may be involved in the proper development of the cardiovascular system.
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    Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems

    Original price was: $199.00.Current price is: $150.00.

    Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems

    by Antonio Giordano (Editor), Umberto Galderisi (Editor)
    Complex physiopathological relationships have been proven to exist between two of the body’s most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another. The text looks at several aspects of the cardiovascular and nervous systems from a new point of view, describing the differences and similarities in their differentiation pathways with an emphasis on the role of cell cycle regulation and cell differentiation. Topics discussed include neurogenesis in the central nervous system, neural stem cells, and the basic-helix-loop-helix transcription factors in neural differentiation. Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.
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    Horizons in World Cardiovascular Research Volume 3

    Original price was: $206.00.Current price is: $150.00.

    Horizons in World Cardiovascular Research Volume 3

  • Sale!

    Practical Cardiovascular Pathology 3rd Edition

    Original price was: $191.00.Current price is: $150.00.

    Practical Cardiovascular Pathology 3rd Edition

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    Applications of Biotechnology in Cardiovascular Therapeutics

    Original price was: $189.00.Current price is: $150.00.

    Applications of Biotechnology in Cardiovascular Therapeutics

    For physicians, surgeons, and scientists working on cardiovascular disorders, Applications of Biotechnology in Cardiovascular Therapeutics serves as an invaluable reference by collecting the essential writings of Dr. Kewal K. Jain on the topics of biotechnology as they relate to cardiovascular disease.  This thorough volume includes such subjects as biotechnology and therapeutic delivery to the cardiovascular system, cell-selective targeted drug delivery, cell and gene therapies, including antisense and RNA interference, cutting-edge gene therapy approaches, as well as personalized cardiology as a way of integrating new technologies into the selection of the best possible treatment for an individual patient.  Selected references from recent literature are collected for each chapter, and the text is supplemented by a variety of useful tables and figures. Comprehensive and up-to-date, Applications of Biotechnology in Cardiovascular Therapeutics will be tremendously useful for those working in life sciences and the pharmaceutical sciences, and the inclusion of some basics of cardiovascular diseases will greatly benefit nonmedical readers as well.
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    Genes and Cardiovascular Function

    Original price was: $203.00.Current price is: $150.00.

    Genes and Cardiovascular Function

    by Bohuslav Ostadal (Editor), Makoto Nagano (Editor), Naranjan S. Dhalla (Editor) Rapid advances in molecular medicine have led to pronounced new developments in experimental and clinical cardiology.  In the embrace of modern molecular biology and bridging the gap between the clinical and the genomic, cardiovascular medicine has seen major strides in the understanding of the molecular mechanisms that drive disease progression.  The ability to rapidly identify candidate human genes for cardiovascular diseases lends itself to the development of diverse strategies for disease treatment and management.  The wide variety of gene expressions proffers excellent targets for novel therapeutics.  Gene therapy is steadily increasing in viability and represents a fascinating arena of research and clinical focus. This book is based on two international Mendel symposia on “Genes and the Heart,” joint meetings of the Japanese and European sections of the International Academy of Cardiovascular Sciences.  Highlighting selected symposia contributions, this book explores the role of molecular biology and genetics in the basic knowledge, genesis, and clinical interventions of cardiovascular diseases.
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    Nutritional and Metabolic Bases of Cardiovascular Disease

    Original price was: $199.00.Current price is: $150.00.

    Nutritional and Metabolic Bases of Cardiovascular Disease

    Extraordinary advances in the understanding of the links between nutrition, metabolism, and cardiovascular disease have prompted a systematic reappraisal of knowledge in the field. As a result, it is now imperative that clinicians who care for patients with CVD or its key risk factors have a solid understanding of the often complex interrelationships between cardiovascular health and chronic diseases such as diabetes and obesity.Written by a team of international thought leaders in cardiology, endocrinology, diabetology and nutritional science, this important new book:
    • Examines and updates the role of obesity, hyperlipidemia, diabetes, hypertension, thrombosis, and aging in atherogenesis
    • Describes in detail the scientific and clinical evidence of the etiopathogenesis of ischemic heart disease as well as of peripheral and cerebrovascular disease
    • Focuses on the 6 topics that will be of greatest interest to readers: 1) general nutrition, 2) metabolic syndrome and diabetes, 3) hyperlipidemia and atherosclerosis, 4) hypertension and cerebrovascular disease, 5) hemostasis and thrombosis, 6) aging
    Throughout the book, in clear and accessible text, contributors illuminate the close relationship between dietary habits, the metabolic processes of nutrients, and their impact on the cardiovascular system, always with an eye on how the physician can use this information to implement better cardiovascular prevention and improve  patient care. Nutritional and Metabolic Bases of Cardiovascular Disease is ideal for those who need to update their knowledge of the links between nutrition, metabolism and CVD, from trainees, clinicians and clinical investigators in cardiovascular medicine to endocrinologists, diabetologists, and nutritionists.
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    Cardiovascular Risk Factors

    Original price was: $203.00.Current price is: $150.00.

    Cardiovascular Risk Factors

    Cardiovascular risk factors contribute to the development of cardiovascular disease from early life. It is thus crucial to implement preventive strategies addressing the burden of cardiovascular disease as early as possible. A multidisciplinary approach to the risk estimation and prevention of vascular events should be adopted at each level of health care, starting from the setting of perinatology. Recent decades have been marked with major advances in this field, with the emergence of a variety of new inflammatory and immune-mediated markers of heightened cardiovascular risk in particular. The current book reflects some of the emerging concepts in cardiovascular pathophysiology and the shifting paradigm of cardiovascular risk estimation. It comprehensively covers primary and secondary preventive measures targeted at different age and gender groups. Attention is paid to inflammatory and metabolic markers of vascular damage and to the assessment of vascular function by noninvasive standardized ultrasound techniques. This is a must-read book for all health professionals and researchers tackling the issue of cardiovascular burden at individual and community level. It can also serve as a didactic source for postgraduate medical students.
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    Diabetes in Cardiovascular Disease A Companion to Braunwalds Heart Disease

    Original price was: $189.00.Current price is: $150.00.
    Colour Matt Finshed
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    Diagnostic Imaging Cardiovascular 2nd Ed

    Original price was: $209.00.Current price is: $150.00.

    Diagnostic Imaging Cardiovascular 2nd Ed

    "Written by many of the best-known names in cardiac and vascular imaging, Diagnostic Imaging: Cardiovascular, 2nd edition contains a vast amount of concentrated information about cardiovascular disease entities and numerous high quality state of the art images. Unlike other cardiovascular imaging textbooks this text focuses not just on one imaging modality such as MRI or CT, but rather highlights the imaging findings and appropriate role of all current imaging modalities that are pertinent to individual diagnoses. The imaging material is superb throughout and the author list includes experts from all aspects of modern cardiac and vascular imaging. Images are clear and convey typical and atypical examples of specific diagnoses as well as "mimics" and potential pitfalls that may affect diagnostic accuracy. As the 2nd edition to Diagnostic Imaging: Cardiovascular, the reader can expect the most up-to-date information. This is a must-have new edition!. Published by Amirsys, a globally recognized medical information publisher. Authored by the leading experts in cardiovascular imaging within radiology and cardiology. Unique case based format is complimented by prosaic introduction to categories of disease entities and by detailed anatomic reviews. Heavily illustrated along with hundreds of annotated images.
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    Management of Cardiovascular Disease in Women

    Original price was: $205.00.Current price is: $150.00.

    Management of Cardiovascular Disease in Women

    by Hanna Z. Mieszczanska (Editor), Gladys P. Velarde (Editor)
    Cardiovascular disease is the leading cause of death in women in the US, with more women dying from heart disease than men. Women may have different presentation from men and often need a different approach to diagnosis and treatment. There are also unique topics of management of heart disease in women, including issues during pregnancy, lactation, and menopause. Many different health care providers, as well as cardiologists are involved in treating these patients. A manual reviewing diagnosis and treatment of cardiac disease in women would help providers without specific cardiology training to deliver care with greater efficiency. A practical and comprehensive guide geared towards these providers would be a highly practical and valuable resource that would be utilized in everyday practice in offices that include urban clinics, general medicine offices, obstetrics and gynecology offices, as well as in the surgical subspecialties. This book will be a highly practical resource that can be directly applied to the issues that arise in everyday practice. There is no available book on the market that focuses on a broader approach to cardiac disease in women or focuses on non-cardiology providers (and their trainees) who have the need to know more about treatment of cardiovascular disease in women.
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    Dietary Risk Factors Of Cardiovascular Diseases

    Original price was: $204.00.Current price is: $150.00.

    Dietary Risk Factors Of Cardiovascular Diseases

    Although successful efforts have been greatly exerted to prevent and treat cardiovascular diseases (CVDs), it currently causes the most number of global deaths among all kinds of diseases. This book has comprehensively reviewed dietary risk factors for CVDs. There are several approved dietary risk factors for CVDs in our daily diets and foods. The dietary risk factors include toxicities caused by an over-consumption of cholesterol, energy, saturated fatty acids, saccharides (especially fructose), iron, sodium, alcohol, niacin, homocysteine, alkaloids (such as synephrines, caffeine, tyramine, dopamine, histamine, and cyanide), nucleic acids and trans-fatty acids. Other extensive factors include the metabolites of choline-containing compounds or L-carnitine, and environmental contaminants such as mercury and cadmium; the deficiencies of folate and vitamins D, B6, or B12; the toxicity or deficiency of magnesium; and the consumption of sweetened soft drinks. Underweight, or even normal weight individuals might not decrease the occurrence of cardiovascular diseases because the deficiency of some nutrients, and alkaloids in the above mentioned chapters that are able to control weight could also damage the cardiovascular system. It seems that the association of all these risk factors in blood with CVDs has been well established, though some controversial opinions on some risk factors exist. Therefore, it should be worth carrying out further studies on the correlation of these risk factors in foods with the occurrence of CVDs.

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    Clinico Pathological Atlas of Cardiovascular Diseases

    Original price was: $207.00.Current price is: $150.00.

    Clinico Pathological Atlas of Cardiovascular Diseases

    by Joaquín S. Lucena (Editor), Pablo García-Pavía (Editor), M. Paz Suarez-Mier (Editor), Luis A. Alonso-Pulpon (Editor)
    The objective of this Atlas is to contribute to the knowledge of morphological findings of the main cardiovascular diseases among the various specialists who deal with people affected of heart diseases: cardiologists and cardiovascular surgeons, clinical and forensic pathologists, coroners, sports medicine doctors. The interest in cardiovascular pathology, neglected for years in many countries, is increasing worldwide and we are witnessing the revitalization of a discipline, which, in collaboration with clinicians, is making great contributions to the fight against heart diseases and sudden-unexpected deaths. This atlas of cardiovascular diseases is the result of close collaboration between Spanish specialists in cardiology and in cardiovascular pathology and describes the clinical and pathologic features (gross and histopathologial) of major cardiovascular diseases in adults, especially those acquired, but also treat relevant congenital anomalies. This book contains 635 images, 78 tables and graphics distributed in 12 chapters across the spectrum of diseases that can be found in each of the structures of the cardiovascular system (aorta, pulmonary vessels, coronaries, valves, myocardium, pericardium and conduction system). The coordinated work of forensic pathologists from different cities in Spain and cardiologists (primarily from the Hospital Universitario Puerta de Hierro de Madrid) has assembled in all chapters their two worlds (forensic pathology and cardiology) to achieve a practical work with the aim to serve as a practical tool for multiple specialists.
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    Cardiovascular Imaging Arterial and Aortic Valve Inflammation and Calcification

    Original price was: $199.00.Current price is: $150.00.

    Cardiovascular Imaging Arterial and Aortic Valve Inflammation and Calcification

    by Elena Aikawa (Editor) 
    This book provides comprehensive reviews on our most recent understanding of the molecular and cellular mechanisms underlying atherosclerosis and calcific aortic valve disease (CAVD) as visualized in animal models and patients using optical molecular imaging, PET-CT, ultrasound and MRI. In addition to presenting up-to-date information on the multimodality imaging of specific pro-inflammatory or pro-calcification pathways in atherosclerosis and CAVD, the book addresses the intriguing issue of whether cardiovascular calcification is an inflammatory disease, as has been recently supported by several preclinical and clinical imaging studies. In order to familiarize researchers and clinicians from other specialties with the basic mechanisms involved, chapters on the fundamental pathobiology of atherosclerosis and CAVD are also included. The imaging chapters, written by some of the foremost investigators in the field, are so organized as to reveal the nature of the involved mechanisms as disease progresses.
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    Manual of Cardiovascular Proteomics

    Original price was: $199.00.Current price is: $150.00.

    Manual of Cardiovascular Proteomics

    by Giulio Agnetti (Editor), Merry L. Lindsey (Editor), D. Brian Foster (Editor)This book fulfils the need to keep up with the high number of innovations in proteomics, and at the same time to warn the readers about the danger of manufacturers and scientists claims around new technologies. Mass spectrometry stands as the core technology in proteomics. The emerging field of targeted proteomics and its potential applications in the cardiovascular arena are also reviewed and discussed. A concluding section highlights the promise of proteomics in the light of these recent developments.​ As this technique and its applications have undergone remarkable advances in the past years, recent updates on proteomic applications are covered. Another key concept revealed by proteomic technologies is that the extent of protein post-translational modifications (PTMs) as well as their impact on the phenotype has been underestimated by pre-proteomics science. As such, part of the manual focuses on the emerging role of PTMs in basic cardiovascular sciences and in the clinics. In fact, there is an emerging consensus that the detailed annotation of protein PTMs could lead to a more in-depth representation of biological systems, translating into more specific targets for therapy as well as biomarkers. Moreover, a recent trend is so-called “targeted proteomics”. The approach was awarded the title of “Method of the Year” by Nature in 2013 (see the editorial by Vivien Marx in 1st issue of Nature in Jan 2013). According to a few proteomic scientists the emphasis should not be placed on generating long lists of proteins but lists of proteins with a true biological meaning. 
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    Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical Part 1

    Original price was: $196.00.Current price is: $150.00.

    Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical Part 1

    The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, etc.
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    Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical Part 2

    Original price was: $196.00.Current price is: $150.00.

    Exercise for Cardiovascular Disease Prevention and Treatment From Molecular to Clinical Part 2

    The book provides an intensive overview on exercise for cardiovascular disease prevention and treatment, from basic research to clinical practice. The volume firstly summarizes the acute and chronic response to exercise. Secondly, evidence for exercise as medicine for the heart based on clinical studies and basic research is summarized. Thirdly, molecular mechanisms mediating the beneficial effects of exercise including IGF-1-PI3K-AKT signalling, NO signalling, C/EBPB-Cited4 signalling, Non-coding RNAs, epigenetic regulators, mitochondria adaption and exosomes are presented. Finally, exercise dosing, prescription and future prospects are provided. This book will provide valuable reference for researchers in cell biology, physiology, as well as physician, physical therapist in cardiology, sport medicine, et
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    Complexity and Nonlinearity in Cardiovascular Signals

    Original price was: $201.00.Current price is: $150.00.

    Complexity and Nonlinearity in Cardiovascular Signals

    by Barbieri (Author), Riccardo Barbieri (Editor), Enzo Pasquale Scilingo (Editor), Gaetano Valenza (Editor) This book reports on the latest advances in complex and nonlinear cardiovascular physiology aimed at  obtaining reliable, effective markers for the assessment of heartbeat, respiratory, and blood pressure dynamics. The chapters describe in detail methods that have been previously defined in theoretical physics such as entropy, multifractal spectra, and Lyapunov exponents, contextualized within physiological dynamics of cardiovascular control, including autonomic nervous system activity. Additionally, the book discusses several application scenarios of these methods. The text critically reviews the current state-of-the-art research in the field that has led to the description of dedicated experimental protocols and ad-hoc models of complex physiology. This text is ideal for biomedical engineers, physiologists, and neuroscientists.
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    Atlas of Acquired Cardiovascular Disease Imaging in Children

    Original price was: $199.00.Current price is: $150.00.

    Atlas of Acquired Cardiovascular Disease Imaging in Children

    by Randy Ray Richardson, MD (Author)
    This atlas is a concise visual guide to the imaging of acquired heart disease in infants, children, and adolescents. Imaging plays an ever-increasing vital role in diagnosis, preoperative planning, and postoperative management for children with these disorders. The book reviews techniques for lowering radiation, discusses protocols for imaging in children, and provides recommendations for the most appropriate studies that decrease the time and cost of imaging these patients. Focusing on functional and anatomic imaging with an emphasis on three-dimensional color-coded models derived from CT and MR scans, this book promotes understanding of cardiovascular disorders in children, including infectious, neoplastic, and metabolic diseases. Atlas of Acquired Cardiovascular Disease Imaging in Children is a valuable resource through which cardiologists, radiologists, pediatric cardiothoracic surgeons, and residents can improve the quality and treatment of pediatric and adolescent patients with acquired heart diseas
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    Prevention and Treatment of Cardiovascular Disease Nutritional and Dietary Approaches

    Original price was: $195.00.Current price is: $150.00.

    Prevention and Treatment of Cardiovascular Disease Nutritional and Dietary Approaches

    This book discusses all aspects of non-pharmacologic approaches to primary and secondary CVD prevention. It highlights the strength of evidence for particular diet styles in CVD prevention, including plant-based diets, the Mediterranean diet, the DASH diet, and low-carbohydrate diets. Chapters present evidence and future directions for diet and nutrition in diseases related to CVD, such as dyslipidemia, cardiometabolic disease (pre-diabetes, the metabolic syndrome, type-2 diabetes mellitus), and obesity. Finally, the book reviews novel and emerging aspects of dietary intervention in CVD prevention, such as dietary approaches to inflammation and the role of the microbiome in CVD.Up-to-date, evidence-based, and clinically oriented, Prevention and Treatment of Cardiovascular Disease: Nutritional and Dietary Approaches is an essential resource for physicians, residents, fellows, and medical students in cardiology, clinical nutrition, family medicine, endocrinology, and lipidology